NIGHT CREAM 554

Best-selling night cream by Dr. Patricia Delarive. A highly concentrated, all-in-one expert formula that plumps, stimulates, smooths, protects, and nourishes the skin.

CHF 125.00
Size 50ml
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High-performance expert cream developed for skin that is gradually losing firmness, density, and radiance. It targets the main visible signs of aging by sustainably improving skin quality.

NIGHT CREAM 554 stimulates the skin's natural regeneration mechanisms to restore its structure, suppleness, and evenness.

Its EXCLUSIVE PHYTO-HORMONE COMPLEX promotes fibroblast activity and supports the natural production of collagen and elastin to enhance skin density and firmness.

At the same time, HPR RETINOL, a highly tolerated next-generation retinoid, accelerates cell renewal to smooth wrinkles and fine lines, refine skin texture, and reveal a more even complexion. The formula is completed by biomimetic active ingredients that intensely nourish the skin, strengthen its skin barrier, and sustainably preserve its comfort.

Day after day, the skin appears denser, firmer, and smoother. Wrinkles and fine lines are reduced, the complexion regains more radiance, and the overall quality of the skin is sustainably improved.

Rich texture, for optimal skin comfort.

All skin types • Silicone-free

On clean, dry skin, apply daily to the face, neck and décolleté, avoiding the eye area.

• EXCLUSIVE PHYTOHORMONE COMPLEX
Exclusive combination of plant extracts, notably black cohosh, red clover and yarrow. It stimulates fibroblast activity and supports neocollagenesis as well as the natural production of elastin, contributing to strengthening skin density, firmness and elasticity.
• 1.5% HPR RETINOL (HYDROXYPINACOLONE RETINOATE)
Highly tolerant next-generation retinoid that accelerates cell renewal. It helps smooth wrinkles and fine lines, refine skin texture and gradually improve skin tone evenness.
• CERAMIDE NP
Strengthens the skin barrier, helps limit water loss and durably improves skin comfort.
• SQUALANE
Biomimetic lipid that nourishes the skin, restores its suppleness and helps maintain optimal hydration.
• SHIKONINE
Plant-based active with antioxidant and soothing properties. It helps protect the skin against oxidative stress and helps maintain its balance.
• VITAMINS C & E
Powerful antioxidants that help protect the skin from free radicals responsible for premature skin aging and help preserve its radiance.

  • Stimulates collagen and elastin production
  • Smooths wrinkles and fine lines
  • Firms and plumps the skin
  • Intensely nourishes and strengthens the skin barrier
  • Long-lasting improvement in skin quality

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NIGHT CREAM 554

Reactivation of the skin's natural mechanisms, including collagen production, to restore density and elasticity. Provided by our exclusive phyto-hormone complex , which mimics the effects of female hormones and firms the skin while redefining the oval of the face.

Smoothing of wrinkles and fine lines and skin regeneration, without irritation. Provided by HPR retinol (Hydroxypinacolone Retinoate) , a latest-generation retinoid that stimulates cell renewal while being well tolerated. It reduces wrinkles, refines skin texture and evens out the complexion.

Strengthens, soothes and revives the skin's natural radiance. Provided by shikonin and squalane , which protect against oxidative stress, restore hydration and strengthen the skin barrier for brighter and more comfortable skin.

PRINCIPES ACTIFS

PHYTOHORMONES

An exclusive combination of plant extracts that mimics certain skin effects of estrogens and progesterone to stimulate fibroblast activity, boost collagen production, and improve firmness.

RETINOL HPR 1.5%

Next-generation direct-acting retinoid, with no conversion required. Non-irritating and non-photosensitizing, it can be used morning and evening.It stimulates skin renewal, helps smooth wrinkles and fine lines, and refines skin texture.

SQUALANE

A biomimetic lipid naturally present in the skin, it nourishes and helps maintain optimal hydration without a greasy feel. It supports the skin barrier and limits water loss, for softer, more comfortable skin that is nourished long-lasting.

SHIKONINE

Plant-based active ingredient with antioxidant and soothing properties, which helps protect the skin from oxidative stress, relieves discomfort, and preserves its balance. It supports the skin's natural regeneration mechanisms for a more resilient and visibly soothed complexion.

AQUA, CETEARYL ALCOHOL, PRUNUS AMYGDALUS DULCIS OIL, CAPRYLIC/CAPRIC TRIGLYCERIDE, GLYCERIN, ETHYLHEXYLGLYCERIN, HYDROGENATED COCO-GLYCERIDES, SQUALANE, DIISOPROPYL ADIPATE, HYDROGENATED STARCH HYDROLYSATE, CETYL ALCOHOL, ROSA DAMASCENA FLOWER EXTRACT, ACHILLEA MILLEFOLIUM EXTRACT, PUNICA GRANATUM FRUIT EXTRACT, DIOSCOREA JAPONICA ROOT EXTRACT, CIMICIFUGA RACEMOSA ROOT EXTRACT, LITHOSPERMUM ERYTHRORHIZON ROOT EXTRACT, TRIFOLIUM PRATENSE LEAF EXTRACT, ZIZYPHUS JUJUBA FRUIT EXTRACT, PAPAVER RHOEAS PETAL EXTRACT, HYDROXYPINACOLONE RETINOATE, CERAMIDE NP, TOCOPHEROL, ASCORBYL PALMITATE, ASCORBIC ACID, PROPYLENE GLYCOL, CITRIC ACID, HYDROGENATED RAPESEED OIL, HELIANTHUS ANNUUS SEED OIL, PROPANEDIOL, SODIUM STEAROYL GLUTAMATE, CARBOMER, SODIUM POLYACRYLATE, ALCOHOL, CAPRYLYL GLYCOL, 1,2-HEXANEDIOL, BENZOIC ACID, DEHYDROACETIC ACID, PHENOXYETHANOL, PARFUM, TETRAMETHYL ACETYLOCTAHYDRONAPHTHALENES, TRIMETHYLBENZENEPROPANOL

Dr. DELARIVE RESPONDS

From the age of 30, cellular metabolism gradually slows down. The natural production of collagen, elastin, and hyaluronic acid decreases, which directly impacts the density and firmness of the skin. This phenomenon is accentuated in women by the decline in hormones, which strongly influences skin balance.

A targeted biostimulation approach can then make the difference: by reactivating fibroblasts, certain active ingredients such as peptides or phyto-hormones (particularly in women) can restart collagen production, improve skin elasticity and gradually redefine volumes.

Not necessarily. It all depends on the form. HPR (Hydroxypinacolone Retinoate), used in some new-generation formulas, is a retinoid that's particularly well-tolerated, even by sensitive skin. It provides all the recognized effects of retinol—cell renewal, wrinkle reduction, and improved skin texture—without the typical irritation associated with more aggressive retinoids.

Phytohormones are plant extracts capable of mimicking some of the effects of female hormones on the skin, particularly estrogen. They are of major interest in anti-aging cosmetics: they help boost collagen production, improve elasticity, and strengthen skin density, particularly in women over the age of 30, when hormone levels begin to decline.

Exfoliation works on the surface, often in a one-off manner. Resurfacing, on the other hand, goes further: it actively stimulates deep cell renewal. Thanks to active ingredients like HPR retinol, it not only smooths the skin, but also reduces wrinkles, evens out skin tone, and regenerates the skin as a whole.

Not at all. It's not the number of steps that matters, but the quality of the formulas and their synergy. A short, well-thought-out routine with all-in-one treatments concentrated in dermatological active ingredients can be more effective than a series of poorly adapted products. The key is to act on the key dimensions of skin aging: stimulation, regeneration, and protection.

There is no single miracle ingredient, but several families of complementary active ingredients.

Retinoids (such as HPR retinol) stimulate cell renewal and improve skin texture. Peptides work deep down to boost the synthesis of collagen and support fibers. Antioxidants, such as vitamin C, vitamin E, and shikonin, protect the skin from oxidative stress, which is responsible for premature aging.

Gentle exfoliants, such as glycolic acid or salicylic acid, help remove dead skin cells, smooth skin texture, and revive radiance. Finally, phytohormones help compensate for the decline in hormones in women over 30 by reactivating key skin functions.