



NIGHT CREAM 554
The bestseller by Dr. Patricia Delarive, an expert formula designed to deliver visibly denser, firmer and smoother skin.
NIGHT CREAM 554 is the most concentrated treatment in the range, specially formulated to intensely stimulate cell renewal and strengthen skin density during the night, when the skin regenerates best.
Its unique formula combines powerful active ingredients with complementary effects:
✔ The exclusive phytohormone complex stimulates fibroblast activity and natural collagen production to deeply redensify the skin, improve its elasticity, and strengthen its support structure. The result: firmer, denser, and firmer skin.
✔ HPR Retinol (1.5%) – a 4th generation retinoid – directly stimulates the production of collagen and elastin, accelerates cell renewal and smoothes wrinkles and fine lines, without irritating.
✔ Squalane, a biomimetic lipid naturally present in the skin, strengthens the skin barrier, maintains hydration and protects against external aggressions. It intensely nourishes the skin while providing comfort and suppleness.
All-in-one, this night cream redensifies, firms, smoothes, repairs, nourishes and protects the skin in depth, for visibly rested features upon waking and a more even texture.
Suitable for all women aged 35 and over and for all skin types, including sensitive skin.
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NIGHT CREAM 554
Reactivation of the skin's natural mechanisms, including collagen production, to restore density and elasticity. Provided by our exclusive phyto-hormone complex , which mimics the effects of female hormones and firms the skin while redefining the oval of the face.
Smoothing of wrinkles and fine lines and skin regeneration, without irritation. Provided by HPR retinol (Hydroxypinacolone Retinoate) , a latest-generation retinoid that stimulates cell renewal while being well tolerated. It reduces wrinkles, refines skin texture and evens out the complexion.
Strengthens, soothes and revives the skin's natural radiance. Provided by shikonin and squalane , which protect against oxidative stress, restore hydration and strengthen the skin barrier for brighter and more comfortable skin.
Dr. DELARIVE RESPONDS
From the age of 30, cellular metabolism gradually slows down. The natural production of collagen, elastin, and hyaluronic acid decreases, which directly impacts the density and firmness of the skin. This phenomenon is accentuated in women by the decline in hormones, which strongly influences skin balance.
A targeted biostimulation approach can then make the difference: by reactivating fibroblasts, certain active ingredients such as peptides or phyto-hormones (particularly in women) can restart collagen production, improve skin elasticity and gradually redefine volumes.
Not necessarily. It all depends on the form. HPR (Hydroxypinacolone Retinoate), used in some new-generation formulas, is a retinoid that's particularly well-tolerated, even by sensitive skin. It provides all the recognized effects of retinol—cell renewal, wrinkle reduction, and improved skin texture—without the typical irritation associated with more aggressive retinoids.
Phytohormones are plant extracts capable of mimicking some of the effects of female hormones on the skin, particularly estrogen. They are of major interest in anti-aging cosmetics: they help boost collagen production, improve elasticity, and strengthen skin density, particularly in women over the age of 30, when hormone levels begin to decline.
Exfoliation works on the surface, often in a one-off manner. Resurfacing, on the other hand, goes further: it actively stimulates deep cell renewal. Thanks to active ingredients like HPR retinol, it not only smooths the skin, but also reduces wrinkles, evens out skin tone, and regenerates the skin as a whole.
Not at all. It's not the number of steps that matters, but the quality of the formulas and their synergy. A short, well-thought-out routine with all-in-one treatments concentrated in dermatological active ingredients can be more effective than a series of poorly adapted products. The key is to act on the key dimensions of skin aging: stimulation, regeneration, and protection.
There is no single miracle ingredient, but several families of complementary active ingredients.
Retinoids (such as HPR retinol) stimulate cell renewal and improve skin texture. Peptides work deep down to boost the synthesis of collagen and support fibers. Antioxidants, such as vitamin C, vitamin E, and shikonin, protect the skin from oxidative stress, which is responsible for premature aging.
Gentle exfoliants, such as glycolic acid or salicylic acid, help remove dead skin cells, smooth skin texture, and revive radiance. Finally, phytohormones help compensate for the decline in hormones in women over 30 by reactivating key skin functions.